Tumors are often heterogeneous with respect to many features. My research focuses on identifying sources of heterogeneity and determining how such heterogeneity impacts prevention and treatment. Novel concepts are being tested with a unique experimental platform consisting of recently developed animal models and state-of-the-art imaging. The results could potentially shift current paradigms in cancer biology.
Department
Hess, Gaelen
Hoon, Mrinalini
Huttenlocher, Anna
Cell migration and chemotaxis, adhesive mechanisms that regulate cell migration and the role of integrin signaling
Iyer, Gopal
1. Genomics and Molecular Imaging of Lung-Brain Metastasis
2. Defining the functional significance of bromodomain containing proteins in pan-cancer studies.
Johannsen, Eric
Jones, Mathew
Kang, Junsu
The capacity for complex tissue regeneration is unevenly distributed across species. Unlike human, zebrafish possess a remarkable potential to regenerate tissues such as amputated appendages and damaged heart muscles. Interest of my laboratory is to understand how and what genetic and epigenetic factors control tissue regeneration using adult zebrafish as a model system.
Kenney, Shannon
Understanding the molecular regulation and pathogenesis of the human herpesvirus; Epstein-Barr virus (EBV)
Kimple, Michelle
Guanine Nucleotide Binding Proteins, pancreatic beta-cell biology, insulin secretion, diabetes pathophysiology