Position title: Assistant Professor
Phone: (608) 890-3018
1111 Highland Avenue
West Wedge 2768
Madison, WI 53703
PhD Harvard University
High-throughput functional genomics to investigate DNA repair, transcriptional regulation, and pathogenic effectors
We use high-throughput screening platforms and next-generation sequencing to perform functional genomics in mammalian cells. We use these technologies to explore how genotypes are related to human health, including disease state and treatment response. These tools are broadly applicable, but our lab uses them to explore mammalian DNA repair and transcriptional regulation, common targets for therapeutic intervention in cancer. In addition to identifying new machinery, we investigate how host and pathogenic factors perturb these processes and alter the response to therapeutic strategies.