Transcriptional control of normal cardiovascular development and function
Chromatin Dynamics in Development and Cancer
Vascular diseases, cell apoptosis, inflammation, signaling, adult progenitor cells, gene therapy
Cardiac regeneration, Transcriptional control of cardiomyocyte cell cycle, Nerve regulation of heart regeneration
Dr. Douglas McNeel, MD PhD is a genitourinary medical oncologist with a translational laboratory research focus on prostate cancer immunology. Since 1997 he and his laboratory have studied vaccines for prostate cancer, specifically identifying antigens to target in vaccines, evaluating DNA vaccines in murine models to elicit tumor-reactive CD8+ T cells, and translating these studies to human clinical trials.
Immunomodulation of the tumor microenvironment with radiation therapy; novel approaches to in situ cancer vaccination