Jeniel Nett

Credentials: MD, PhD

Position title: Assistant Professor

Email: jenett@medicine.wisc.edu

Phone: (608) 262-7494

Address:
Microbial Sciences Building
1550 Linden Dr
Madison, WI 53706

Lab
Nett Lab Website

Focus Groups

Immunology/Immunopathology

Education

MD, University of Wisconsin-Madison

PhD, Cellular and Molecular Biology, University of Wisconsin-Madison

Molecular Mycology, Marine Biology Laboratory, Woods Hole MA

Research Summary

The host response to biofilm infections, with the goal of devising new approaches for diagnosis and treatment of these common infections.

Research Detail

My research focuses on the host response to biofilm infections, with the goal of devising new approaches for diagnosis and treatment of these common infections. Patients with indwelling medical devices, such as venous catheters, are at risk for invasive disease caused by various fungal and bacterial pathogens. In these patients, organisms adhere to the device surface and proliferate as a biofilm of resilient cells encased in an extracellular matrix. As the host immune system and conventional anti-infectives are often not capable of eradicating biofilms, these infections can have devastating consequences. Our laboratory studies Candida, the most common nosocomial fungal pathogen, and how the transition to the biofilm lifestyle protects Candida from immune clearance.

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