Guanine Nucleotide Binding Proteins, pancreatic beta-cell biology, insulin secretion, diabetes pathophysiology
The Lamming laboratory’s goal is to understand how nutrient-responsive signaling pathways can be harnessed to promote health and longevity.
Assay and biomarker development
Drug development for solid tumors
Dr. Douglas McNeel, MD PhD is a genitourinary medical oncologist with a translational laboratory research focus on prostate cancer immunology. Since 1997 he and his laboratory have studied vaccines for prostate cancer, specifically identifying antigens to target in vaccines, evaluating DNA vaccines in murine models to elicit tumor-reactive CD8+ T cells, and translating these studies to human clinical trials.
The host response to biofilm infections, with the goal of devising new approaches for diagnosis and treatment of these common infections.
Alzheimer’s disease, neuroimaging, lifestyle, genetics, cognitive resilience
Molecular mechanisms of neurodevelopment and neurodegeneration