John Williams
Credentials: MD
Position title: Professor and Chair
Email: Jvwilliams2@wisc.edu
Website: John Williams's website
Address:
H4/458, 1675 Highland Ave, Madison WI 53792
Education
MD: Virginia Commonwealth University 1994
Research Summary
Respiratory infections are the leading cause of death in children worldwide, and a leading cause of disease in children and adults in developed nations. The focus of our research is the basic and clinical investigation of respiratory viruses.
Research Detail
Our major area of investigation is the immunity and pathogenesis of human metapneumovirus (HMPV). HMPV is a pneumovirus discovered in 2001 that is a leading cause of acute lower respiratory illness in infants, children, the elderly, and persons with underlying medical conditions. There are no licensed antivirals or vaccines for HMPV, and little is known about protective immunity and viral pathogenesis. We seek to understand the immunobiology of this important human pathogen, to elucidate mechanisms of lung CD8+ T cell impairment, and to facilitate the development of preventive and therapeutic strategies.
Publications