Thomas Friedrich

PhD

Associate Professor

thomasf@primate.wisc.edu

(608) 265-3381

Rm 127 555 Science Dr
555 Science Dr
Madison, WI 53711

Focus Groups

Immunology/Immunopathology

Education

PhD, University of Wisconsin

Research Summary

Viral immunity; pathogenesis

Research Detail

Why do we get sick? This simple question underpins all research in my laboratory. Our overarching goal is to understand why immune responses sometimes fail to protect us from acute and chronic viral diseases. We study innate and adaptive immune responses to acute and chronic viral infections and the mechanisms viruses have evolved to subvert them. Through our discoveries, we hope to contribute to the global campaigns against pandemic influenza and AIDS.

Our work focuses on immune responses to viral infection in nonhuman primates. Because monkeys’ physiology, genetics, and immune systems so closely resemble our own, they provide the best possible approximation of human infections. My lab is affiliated with the Wisconsin National Primate Research Center, which provides expert veterinary care and support for the nonhuman primates used in research on campus.

Current research topics include:

  • Determining the contribution of cellular immunity to protection against newly emerging influenza viruses in humans and animal models
  • Understanding immune correlates of “elite control” of immunodeficiency virus infection
  • Identifying novel primate viruses in Africa and assessing their pandemic potential

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