Arjang Djamali
Credentials: MD
Position title: Associate Professor
Email: axd@medicine.wisc.edu
Phone: (608) 270-5681
Address:
5142 MFCB
1685 Highland Ave
Madison, WI 53792
Focus Groups
Immunology/Immunopathology
Signal Transduction
Education
MD, Montpellier Medical School, Montpellier, France
Research Summary
The cellular and molecular mechanisms of fibrogenesis in native and transplant kidney disease
Research Detail
We are interested in examining the cellular and molecular mechanisms of fibrogenesis in native and transplant kidney disease. To this end, we use in vitro, animal and human studies. We are currently investigating the role of Nox and heat shock protein 27 in the pathogenesis of kidney injury. Study models are rat proximal tubular epithelial cells (NRK52E cell line) and murine models of kidney transplantation, unilateral ureteral obstruction and 5/6th nephrectomy. Ongoing translational studies are examining these processes in patients with chronic kidney disease and chronic allograft nephropathy.