Barbara Bendlin

Focus Groups

Neuroscience/Neuropathology

Research Summary

Aging; Alzheimer’s disease, Neurobiology of Disease, Behavior and Cognition

Research Detail

My research interests are centered on understanding what factors lead to successful cognitive aging, and what risk factors are associated with pathological brain aging. My recent work is focused on understanding the effect of factors that contribute to or protect against the development of Alzheimer’s disease (AD). Together with collaborators across campus, my studies enroll people in middle and late age who may be at increased risk for developing AD due to parental family history, genotype, or vascular risk factors. My projects use magnetic resonance imaging (MRI) as a tool to understand the effect of risk on brain blood flow and structure. Additionally, I am funded to examine the relationship between cerebrospinal fluid biomarkers and brain structure to learn more about early mechanisms of brain damage in AD. Learning more about the earliest brain changes involved in AD is expected to lead to earlier diagnosis, prevention, and the development of new therapies for AD.

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