Tim Yoshino

Credentials: PhD

Position title: Professor

Email: yoshinot@svm.vetmed.wisc.edu

Phone: (608) 263-6002

127 Biotron
2115 Observatory Dr
Madison, WI 53706

Focus Groups



PhD, Biology, University of California, Santa Barbara

Postdoctoral, Institute for Pathobiology, Lehigh University

Research Summary

Molecular Parasitology, Schistosomiasis, Parasite-Host Interactions, Mollusc Intermediate Host, Innate Immunity, Pathogen Recognition Receptors, Glycobiology, Neglected Tropical Diseases

Research Detail

Human schistosomiasis is a neglected tropical disease that results from infection by several species of the parasitic flatworm Schistosoma. My research is focused on defining and characterizing the molecular basis for innate resistance and susceptibility of inbred strains of the snail Biomphalaria glabrata to infection by larvae of the human blood fluke Schistosoma mansoni, causative agent of hepatosplenic schistosomiasis. Methods involving cellular and molecular biology, tissue culture, genomics/proteomics and whole organism manipulations are used to define and characterize the innate immune system of the snail host, in order to gain a better understanding of the underlying processes regulating immune resistance to schistosome larval infection.

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